娄智勇，男，1980年出生于天津，清华大学副教授。主要对人类疾病的研究，曾经获得多项个人荣誉奖项，还包括多项代表性论文。 2002年获清华大学基础科学理学学士学位，2007年获清华大学生物学理学博士学位，2007年留校任清华大学医学院讲师，2010年12月任清华大学医学院副教授，娄智勇曾获2006年清华大学医学院学术新秀，2007年清华大学研究生“航天海鹰”学术新秀，2010年SCOPUS青年科学家新人奖等荣誉。 

研究方向 ：

      利用蛋白质晶体学，进行重要致病微生物（禽流感病毒、乙\丙型肝炎病毒、SARS冠状病毒、结核杆菌、EV71病毒、NDM-1“超级细菌”等）及与人类疾病相关蛋白质的结构与功能研究，以及基于结构的药物筛选工作。 

代表性论文： 

1. Crystal Structure of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis. Shan S, Chen X, Liu T, Zhao H, Rao Z and Lou Z*. FASEB J. 2011 Jan 31. [Epub ahead of print] (Corresponding author)
2. The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease. Xue F, Sun Y, Yan L, Zhao C, Chen J, Bartlam M, Li X, Lou Z*, Rao Z.J Virol. 2010 Jul;84(13):6461-71. (Corresponding author)
3. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, Fodor E, Rao Z, Liu Y. Nature. 2009 Apr 16; 458(7240):909-13. (co-first author)
4. Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Leader Protease Nsp1α. Sun Y, Xue F, Guo Y, Ma M, Hao N, Zhang XC, Lou Z*, Li X, Rao Z. J Virol. 2009 Aug 12. (Corresponding author)
5. C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer. Zhong N, Zhang S, Xue F, Kang X, Zou P, Chen J, Liang C, Rao Z, Jin C, Lou Z*, Xia B. Protein Sci. 2009 Apr;18(4):839-44. (Corresponding author)
6. Structural basis for the recognition of blood group trisaccharides by norovirus. Cao S, Lou Z, Tan M, Chen Y, Liu Y, Zhang Z, Zhang XC, Jiang X, Li X, Rao Z. J Virol. 2007 Jun;81(11):5949-57. (co-first author)
7. Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10. Su D, Lou Z, Sun F, Zhai Y, Yang H, Zhang R, Joachimiak A, Zhang XC, Bartlam M, Rao Z. J Virol. 2006 Aug;80(16):7902-8. (co-first author)
8. Crystal structure of human pyrroline-5-carboxylate reductase. Meng Z, Lou Z, Liu Z, Li M, Zhao X, Bartlam M, Rao Z. J Mol Biol. 2006 Jun 23;359(5):1364-77. (co-first author)
9. Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core. Xu Y, Lou Z, Liu Y, Pang H, Tien P, Gao GF, Rao Z. J Biol Chem. 2004 Nov 19;279(47):49414-9. (co-first author)
10. Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase complexed with a novel natural tri-peptide inhibitor from venom of Agkistrodon acutus. Lou Z, Hou J, Liang X, Chen J, Qiu P, Liu Y, Li M, Rao Z, Yan G. J Struct Biol. 2005 Dec;152(3):195-203.
11. Crystal structures of Nipah and Hendra virus fusion core proteins. Lou Z, Xu Y, Xiang K, Su N, Qin L, Li X, Gao GF, Bartlam M, Rao Z. FEBS J. 2006 Oct;273(19):4538-47.